Vertigo/Dizziness Date Last Search Run: Jan 14, 2025 Table last updated: Nov 02, 2024 Data last added: Dec 19, 2024

Recommendation		RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION		SUPPORTIVE (Green)	NEUTRAL (Yellow)	AGAINST (Red)	NOT YET GRADED (White)
	1 (strong evidence exists)	Antiemetic (Central) Dimenhydrinate	Lorazepam-IV		Oxygen
	2 (fair evidence exists)		Prediction score
	3 (weak evidence exists)

Interventions

Antiemetic (Central)

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Supportive (Green)	Severity of vertigo	Patient	In-Patient	Saberi A, Pourshafie SH, Kazemnejad-Leili E, Nemati S, Sutohian S, Sayad-Fathi S. Ondansetron or promethazine: Which one is better for the treatment of acute peripheral vertigo? Am J Otolaryngol 2019; 40(1):10-5. Medline

Dimenhydrinate

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Supportive (Green)	Termination of vertigo	Patient	ED-MD	Marill KA., Walsh MJ., Nelson BK. Intravenous lorazepam versus dimenhydrinate for treatment of vertigo in the emergency department: A randomized clinical trial. Ann Emerg Med 2000; 36(4):310-9. Medline

Lorazepam-IV

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Neutral (Yellow)	Termination of vertigo	Patient	ED-MD	Marill KA., Walsh MJ., Nelson BK. Intravenous lorazepam versus dimenhydrinate for treatment of vertigo in the emergency department: A randomized clinical trial. Ann Emerg Med 2000; 36(4):310-9. Medline

Oxygen

Level

Direction

Primary Outcome

Patient/Process

Setting

Reference

Prediction score

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
II	Supportive (Green)	Evaluation of stroke prevalence	Patient	ED-MD	Yu AH, Leung LY, Leung TWH, Abrigo JM, et al. The TriAGe + score for vertigo or dizziness: A validation study in a university hospital emergency department in Hong Kong. Am J Emerg Med. March 2024; 77:39-45. Medline
II	Opposes (Red)	Sensitivity and specificity	Process	Other	Kogej M, Scherzberg J, Schacher S, Berger M, Seidel M, Gräff I. Clinical use of the manchester triage system in patients with dizziness - An observational study in the emergency department. Int Emerg Nurs. March 2024; 73:101403. Medline