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Post-Cardiac Arrest Care

Date Last Search Run: Feb 01, 2022
Table last updated: May 02, 2021
Data last added: Aug 19, 2022

Recommendation RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION   SUPPORTIVE (Green) NEUTRAL (Yellow) AGAINST (Red) NOT YET GRADED (White)
1 (strong evidence exists)    
2 (fair evidence exists)    
3 (weak evidence exists)      


Interventions

Fluid Resuscitation
Level Direction Primary Outcome Patient/Process Setting Reference

Hypothermia
Level Direction Primary Outcome Patient/Process Setting Reference
I Neutral (Yellow) Survival with good functional outcome at one year Patient ICU Moler FW., Silverstein FS., Holubkov R., et al. Therapeutic hypothermia after out-of-hospital cardiac arrest in children. N Engl J Med 2015; 372(20):1898-908. Medline
II Neutral (Yellow) 1 month survival neuro intact Patient PH-Paramedic Matsui S, Hirayama A, Kitamura T, Sobue T, Hayashi T, Takei H, et al. Target Temperature Management and Survival with Favorable Neurological Outcome After Out-of-Hospital Cardiac Arrest in Children: A Nationwide Multicenter Prospective Study in Japan. Ther Hypothermia Temp Manag 2022; 12(1):16–23. Medline
II Neutral (Yellow) Survival with good functional outcome at 1 year Patient Moler FW., Hutchison JS., Nadkarni VM., Silverstein FS., Meert KL., Holubkov R., et al. Targeted Temperature Management After Pediatric Cardiac Arrest Due To Drowning: Outcomes and Complications. Pediatric Critical Care Medicine 2006; 17(8):712-20. Medline

Inotrope
Level Direction Primary Outcome Patient/Process Setting Reference

Optimal Trip Destination
Level Direction Primary Outcome Patient/Process Setting Reference

Oxygen
Level Direction Primary Outcome Patient/Process Setting Reference

Oxygen-titrated
Level Direction Primary Outcome Patient/Process Setting Reference
II Supportive (Green) Mortality Patient ICU Ferguson LP., Durward A., Tibby SM. Relationship between arterial partial oxygen pressure after resuscitation from cardiac arrest and mortality in children. Circulation 2012; 126(3):335-42. Medline
II Neutral (Yellow) Six-month mortality Patient ICU Guerra-Wallace MM., Casey FL 3rd., Bell MJ., Fink EL., Hickey RW. Hyperoxia and hypoxia in children resuscitated from cardiac arrest. Pediatr Crit Care Med 2013; 14(3):e143-8. Medline


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