Neurogenic Shock Date Last Search Run: Jan 14, 2025 Table last updated: May 02, 2021 Data last added: Aug 23, 2019

Recommendation		RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION		SUPPORTIVE (Green)	NEUTRAL (Yellow)	AGAINST (Red)	NOT YET GRADED (White)
	1 (strong evidence exists)		Colloid Infusion
	2 (fair evidence exists)	Aggressive Crystalloids Pressors
	3 (weak evidence exists)

Interventions

Aggressive Crystalloids

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
II	Supportive (Green)	Functional assessment at 1 year	Patient	ICU	Vale FL., Burns J., et al. Combined medical and surgical treatment after acute spinal cord injury: Results of a prospective pilot study to assess the merits of aggressive medical resuscitation and blood pressure management. J Neurosurg 1997; 87:239-246. Medline

Colloid Infusion

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Neutral (Yellow)	Mortality	Patient	ICU	Lewis SR, Pritchard MW, Evans DJ, Butler AR, Alderson P, Smith AF, et al. Colloids versus crystalloids for fluid resuscitation in critically ill people. The Cochrane database of systematic reviews 2018; 8. Medline
II	Supportive (Green)	Functional assessment at 1 year	Patient	ICU	Vale FL., Burns J., et al. Combined medical and surgical treatment after acute spinal cord injury: Results of a prospective pilot study to assess the merits of aggressive medical resuscitation and blood pressure management. J Neurosurg 1997; 87:239-246. Medline

Pressors

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
II	Supportive (Green)	Functional assessment at 1 year	Patient	ICU	Vale FL., Burns J., et al. Combined medical and surgical treatment after acute spinal cord injury: Results of a prospective pilot study to assess the merits of aggressive medical resuscitation and blood pressure management. J Neurosurg 1997; 87:239-246. Medline