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Neonatal Resuscitation

Date Last Search Run: Nov 18, 2024
Table last updated: Nov 02, 2024
Data last added: Oct 06, 2024

Recommendation RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION   SUPPORTIVE (Green) NEUTRAL (Yellow) AGAINST (Red) NOT YET GRADED (White)
1 (strong evidence exists)      
2 (fair evidence exists)  
3 (weak evidence exists)


Interventions

BVM
Level Direction Primary Outcome Patient/Process Setting Reference
II Supportive (Green) Asphyxia-specific mortality rate (ASMR) Patient ED-MD Bang AT., Bang RA., Baitule SB., Reddy HM., Deshmukh MD. Management of Birth Asphyxia in Home Deliverires in Rural Gadchiroli: The effect of two types of birth attendants and of resuscitating with mouth-to-mouth, tube-mask or bag-mask. J Perinatol 2005; 25(Sl):S82-91. Medline

Chest Compressions
Level Direction Primary Outcome Patient/Process Setting Reference

Epinephrine
Level Direction Primary Outcome Patient/Process Setting Reference
III Opposes (Red) 1 year survival Patient ICU O'Donnell A., Rogers Y. Mortality and neurodevelopment outcome for infants receiving adrenaline in neonatal resuscitation. J Pediatr Child Health 1998; 34:551-6. Medline

ETCO2
Level Direction Primary Outcome Patient/Process Setting Reference
II Supportive (Green) Usage rate Patient PH-Paramedic Hartmann K, Calatayud B, Flamm A. Prehospital Use of Waveform Capnography in Intubated Neonates. Prehosp Emerg Care January 2024; 1-4. Medline

Intubation
Level Direction Primary Outcome Patient/Process Setting Reference
II Neutral (Yellow) First pass success Process PH-MD & CCT Lacquiere D, Smith J, Bhanderi N, et al. Early experience in use of videolaryngoscopy by a neonatal pre-hospital and retrieval service. Emerg Med Australas January 2024. Medline
III Supportive (Green) Time to ETI and overall success Patient SIM Szarpak L., Kurowski A., Czyżewski L. Comparison of infant intubation through the TruView EVO2, TruView PCD, and Miller laryngoscope by paramedics during simulated infant cardiopulmonary resuscitation: A randomized crossover manikin study. Am J of Emerg Med 2015; 33:872–875. Medline

LMA (without AW reflexes)
Level Direction Primary Outcome Patient/Process Setting Reference
III Supportive (Green) Successful airway management Patient OR Trevisanuto D., Doglioni N., Gottardi G., Nardo D., Micaglio M., Parotto M. Laryngeal mask: Beyond neonatal upper airway malformations. Arch Dis Child Fetal Neonatal Ed 2013; 98(2):F185-6. Medline

Mechanical Intraosseous Insertion
Level Direction Primary Outcome Patient/Process Setting Reference
II Supportive (Green) Complications Process PH-Paramedic & CCT Joerck C, Wilkinson R, Angiti RR, Lutz T, Scerri L, Carmo KB. Use of Intraosseous Access in Neonatal and Pediatric Retrieval-Neonatal and Pediatric Emergency Transfer Service, New South Wales. Pediatr Emerg Care Nov 2023; 39(11):853-7. Medline

Nasal Ventilation
Level Direction Primary Outcome Patient/Process Setting Reference
III Supportive (Green) Ability to create airway seal Process SIM del Castillo S., Perez C., Ribera S. Nasal route to ventilation during basic cardiopulmonary resuscitation in children under two months of age. Resuscitation 1997; 35:249-52. Medline

Oxygen
Level Direction Primary Outcome Patient/Process Setting Reference

Resuscitation Attempts in Stillbirth
Level Direction Primary Outcome Patient/Process Setting Reference
III Supportive (Green) Survival neurologically intact Patient PH-Paramedic Casalaz D., Marlow N., Speidel B. Outcome of resuscitation following unexpected apparent stillbirth. Arch Dis Child Neonatal Ed 1998; 78:F112-5. Medline
III Supportive (Green) Survival Patient In-Patient Jain L., Ferre C., Vidyasagar D., et al. Cardiopulmonary resuscitation of apparently stillborn infants: Survival and long-term outcome. J Ped 1991;.118:778-82. Medline

Suction
Level Direction Primary Outcome Patient/Process Setting Reference
III Supportive (Green) Time to aspirate set volume Process Kei J., Mebust DP. Comparing the Effectiveness of a Novel Suction Set-up Using an Adult Endotracheal Tube Connected to a Meconium Aspirator vs. a Traditional Yankauer Suction Instrument. J Emerg Med 2017; 52(4):433-437. Medline

Therapeutic hypothermia
Level Direction Primary Outcome Patient/Process Setting Reference
III Neutral (Yellow) Quality of passive cooling Process PH-MD & CCT Leben M., Nolimal M., Vidmar I., Grosek Å . Passive therapeutic hypothermia during ambulance and helicopter secondary neonatal transport in neonates with hypoxic brain injury a 10-year retrospective survey. ChNS 2018; 34(12) 2463-9. Medline


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