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Mild Allergic Reaction

Date Last Search Run: Feb 01, 2022
Table last updated: Dec 09, 2019
Data last added: Sep 14, 2009

Recommendation RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION   SUPPORTIVE (Green) NEUTRAL (Yellow) AGAINST (Red) NOT YET GRADED (White)
1 (strong evidence exists)      
2 (fair evidence exists)      
3 (weak evidence exists)      


Interventions

Diphenhydramine
Level Direction Primary Outcome Patient/Process Setting Reference
I Supportive (Green) Resolution of symptoms Patient ED-MD Lin Y., et al. Improved outcomes in patients with acute allergic syndromes who are treated with combined H1 and H2 antagonists. Ann Emerg Med 2000; 36:462 Medline
I Supportive (Green) Clinically significant relief Patient ED-MD Runge WJ., Martinez JC., Caravati EM., et al. Histamine antagonists in the treatment of acute allergic reactions. Ann Emerg Med 1992; 21(3):237-42. Medline


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