Hyperglycemia Date Last Search Run: Mar 05, 2026 Table last updated: May 02, 2021 Data last added: Feb 01, 2020

Recommendation		RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION		SUPPORTIVE (Green)	NEUTRAL (Yellow)	AGAINST (Red)	NOT YET GRADED (White)
	1 (strong evidence exists)				Point of Care Lactate
	2 (fair evidence exists)
	3 (weak evidence exists)		Fluid Bolus

Interventions

Fluid Bolus

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
III	Neutral (Yellow)	Glucose reduction	Patient	ED-MD	Driver BE.; Olives TD.; Prekker ME.; Miner JR.; Klein LR.,The Association of Emergency Department Treatments for Hyperglycemia with Glucose Reduction and Emergency Department Length of Stay.2017;The Journal of emergency medicine Dec 2017;53(6):791-797 Medline

Point of Care Lactate

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
X	Not Yet Graded (White)	-			Sebastian-Valles F, Sampedro-Nuñez MA, Arranz-Martin JA, et al. Pre- and in-hospital lactate ratio as a predictor of mortality in severe diabetic ketoacidosis: a multicenter prospective cohort study. Eur J Intern Med. January 2026; 106706. Medline