Benzodiazepines
| Level |
Direction |
Primary Outcome |
Patient/Process |
Setting |
Reference |
|
II
|
Supportive (Green)
|
Medicating acute alcohol withdrawal.
|
Patient
|
In-Patient
|
Lebin JA, Mudan A, Murphy CE 4th, Wang RC, Smollin CG. Return Encounters in Emergency Department Patients Treated with Phenobarbital Versus Benzodiazepines for Alcohol Withdrawal. J Med Toxicol 2022; 18(1):4–10. Medline
|
|
II
|
Supportive (Green)
|
Control of agitation from Impact on 1) ED LOS 2) hospital admission alcohol withdrawal.
|
Process
|
ED-MD
|
Levine AR, Thanikonda V, Mueller J, Naut ER. Front-loaded diazepam versus lorazepam for treatment of alcohol withdrawal agitated delirium. Am J Emerg 2021; 44:415–8. Medline
|
|
II
|
Neutral (Yellow)
|
-
|
Patient
|
ED-MD
|
Pistore A, Penney S, Bryce R, Meyer C, Bouchard B. A retrospective evaluation of phenobarbital versus benzodiazepines for treatment of alcohol withdrawal in a regional Canadian emergency department. Alcohol 2022;102:59–65. Medline
|
|
X
|
Not Yet Graded (White)
|
-
|
|
|
Lebin JA, Bass ME, Heard K, Hoppe J, Jacknin G. A Retrospective Evaluation of Adjunctive Phenobarbital vs. Benzodiazepine Alone for the Treatment of Moderate Alcohol Withdrawal in the Emergency Department. J Emerg Med April 2024; 66(4):e516-22. Medline
|