Childbirth/Post Natal Mother Care Date Last Search Run: Jan 14, 2025 Table last updated: Dec 12, 2017 Data last added: Oct 08, 2024

Recommendation		RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION		SUPPORTIVE (Green)	NEUTRAL (Yellow)	AGAINST (Red)	NOT YET GRADED (White)
	1 (strong evidence exists)	Syntocinon	Uterine Massage		Oxygen
	2 (fair evidence exists)		Tranexamic Acid
	3 (weak evidence exists)

Interventions

Oxygen

Level

Direction

Primary Outcome

Patient/Process

Setting

Reference

Syntocinon

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Supportive (Green)	Blood Loss	Patient	In-Patient	Nordstrom L., Fogelstam F., Fridman G., et al. Routine oxytocin in the third stage of labour: A placebo controlled randomised trial. Br J Obstetrics and Gynaecology 1997; 104:781-6. Medline
II	Neutral (Yellow)	Blood loss	Patient	PH-Paramedic	De Silva M, Mizzi G, Potts E, Webb J, Thyer E, Naidoo N. Tranexamic acid versus oxytocin for primary postpartum Haemorrhage in the out-of-hospital setting: A systematic review with implications for rural practice. Aust J Rural Heal. March 2024. Medline

Tranexamic Acid

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
II	Neutral (Yellow)	Blood loss	Patient	PH-Paramedic	De Silva M, Mizzi G, Potts E, Webb J, Thyer E, Naidoo N. Tranexamic acid versus oxytocin for primary postpartum Haemorrhage in the out-of-hospital setting: A systematic review with implications for rural practice. Aust J Rural Heal. March 2024. Medline

Uterine Massage

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Neutral (Yellow)	Blood Loss	Patient	In-Patient	Hofmeyr GJ., Abdel-Aleem H.., Abdel-Aleem MA. Uterine massage for preventing postpartum haemorrhage. Cochrane Database of Systematic Reviews 2013; (4). The Cochrane Library