Chemical Splash/Burn Date Last Search Run: Jan 14, 2025 Table last updated: Dec 12, 2017

Recommendation		RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION		SUPPORTIVE (Green)	NEUTRAL (Yellow)	AGAINST (Red)	NOT YET GRADED (White)
	1 (strong evidence exists)	Narcotic			Dry Dressing
	2 (fair evidence exists)
	3 (weak evidence exists)	Irrigation Skin

Interventions

Dry Dressing

Level

Direction

Primary Outcome

Patient/Process

Setting

Reference

Irrigation Skin

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
III	Supportive (Green)	Interventions required	Process	In-Patient	Cartotto RC., Peters WJ., Neligan PC., et al. Chemical burns. CJS 1996; 39:205-11. Medline
III	Supportive (Green)	Skin toxicity	Patient	ED-MD	Shibata K., Yoshita Y., Matsumoto H. Extensive chemical burns from toluene. Am J Emerg Med 1994; 12:353-355. Medline

Narcotic

Level	Direction	Primary Outcome	Patient/Process	Setting	Reference
I	Supportive (Green)	Analgesia	Patient	PH-Paramedic	Bounes V., Charpentier S., Houze-Cerfon CH., Bellard C., Ducassé JL. Is there an ideal morphine dose for prehospital treatment of severe acute pain? A randomized, double-blind comparison of 2 doses. Am J Emerg Med 2008; 26(2):148-54. Medline
I	Supportive (Green)	Pain relief using the visual analog scale score	Patient	PH-Paramedic	Galinski M., et al. A randomized double-blind study comparing morphine with fentanyl in prehospital analgesia. Am J Emerg Med 2005; 23:114-9. Medline
II	Supportive (Green)	Analgesia	Patient	PH-Paramedic	McKinnon KDL. Prehospital analgesia with nitrous oxide/oxygen. CMA Journal 1981; 125:836-40. Medline
II	Supportive (Green)	Analgesia	Patient	PH-Paramedic	Ricard-Hibon A., Chollet C., Saada S., et al. A quality control program for acute pain management in out-of-hospital critical care medicine. Ann Emerg Med 1999; 34:783. Medline
II	Supportive (Green)	Analgesia	Patient	PH-Paramedic	Ricard-Hibon A., et al. Compliance with a morphine protocol and effect on pain relief in out-of-hospital patients. J Emerg Med 2008; 34:305-10. Medline
III	Supportive (Green)	Patient satisfaction	Patient	PH-Paramedic	Johnson JC., Atherton Gl. Effectiveness of Nitrous Oxide in a rural EMS System. The Journal of Emergency Medicine 1991; 9:45-53. Medline
III	Supportive (Green)	Analgesia	Patient	PH-Paramedic	Peterson TD., Kerns DE. Prehospital Pain Control: Nitrous Oxide Inhalation. Iowa Medicine 1989; 15-7. Medline