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Carbon Monoxide

Date Last Search Run: Jan 14, 2025
Table last updated: May 02, 2021
Data last added: Jan 27, 2021

Recommendation RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION   SUPPORTIVE (Green) NEUTRAL (Yellow) AGAINST (Red) NOT YET GRADED (White)
1 (strong evidence exists)        
2 (fair evidence exists)    
3 (weak evidence exists)    


Interventions

Direct Transport To Hyperbaric Facility
Level Direction Primary Outcome Patient/Process Setting Reference
III Neutral (Yellow) 1 month neurological outcome Patient In-Patient Dean BS., Verdile VP., Krenzelok EP. Coma reversal with cerebral dysfunction recovery after repetitive hyperbaric oxygen therapy for severe carbon monoxide poisoning. Am J Emerg Med 1993; 11(6):616-8. Medline
III Neutral (Yellow) Detection Treatment carbon monoxide Process PH-Paramedic Lueken RJ., Heffner AC., Parks PD. Treatment of severe carbon monoxide poisoning using a portable hyperbaric oxygen chamber. Ann Emerg Med 2006; 48(3):319-22. Medline

Oxygen
Level Direction Primary Outcome Patient/Process Setting Reference
II Supportive (Green) Change in COHb after 1h treatment Patient ED-MD Tomruk O, Karaman K, Erdur B, Armagan HH, Beceren NG, Oskay A, et al. A New Promising Treatment Strategy for Carbon Monoxide Poisoning: High Flow Nasal Cannula Oxygen Therapy. Medical science monitor 2019; 25 605-9. Medline
II Supportive (Green) Carboxyhemoglobin half-life calculation Patient In-Patient Weaver LK., et al . Carboxyhemoglobin half-life in carbon monoxide-poisoned patients treated with 100% oxygen at atmospheric pressure. Chest 2000; 117:801-8. Medline
II Supportive (Green) Carboxyhemoglobin half-life calculation Patient In-Patient Weaver LK., Howe S., Hopkins R., Chan KJ. Carboxyhemoglobin half-life in CO-poisoned patients treated with 100% O2 at atmospheric pressure. Chest 2000; 117:801-8. Medline
III Supportive (Green) Benefit of O2 Process ED-MD Burney RE., Wu SC., Nemiroff MJ. Mass carbon monoxide poisoning: Clinical effects and results of treatment in 184 victims. Ann Emerg Med 1982; 11(8):394-9. Medline
III Supportive (Green) 1 month neurological outcome Patient In-Patient Dean BS., Verdile VP., Krenzelok EP. Coma reversal with cerebral dysfunction recovery after repetitive hyperbaric oxygen therapy for severe carbon monoxide poisoning. Am J Emerg Med 1993; 11(6):616-8. Medline
III Supportive (Green) Resolution of confusion/non-specific neurologic symptoms Patient ED-MD La Fauci G., Weiser G., Steiner IP., Shavit I. Carbon monoxide poisoning in narghile (water pipe) tobacco smokers. CJEM 2012; 14(1):57-9. Medline
X Not Yet Graded (White) Functional of carbon monoxide. Am J Respir Crit Care Med. 2000;161(6):1816-1819 Patient Takeuchi A., Vesely A., Rucker J., et al. A simple "new" method to accelerate clearance of carbon monoxide. Am J Respir Crit Care Med 2000; 161(6):1816-1819. Medline
X Not Yet Graded (White) Functional poisoning by emergency medical services personnel. Prehosp Emerg Care. 2001;5(4):407-410 Patient Ufberg J., Jaslow D., Thom S., Cesner D., Ukasik J. Scene diagnosis of carbon monoxide poisoning by emergency medical services personnel. Prehosp Emerg Care 2001; 5(4):407-410. Medline
X Not Yet Graded (White) Functional use of a water pipe/hookah. Dtsch Arztebl Int. 2014;111(40):674-679 Patient von Rappard J., Schonenberger M., Barlocher L. Carbon monoxide poisoning following use of a water pipe/hookah. Dtsch Arztebl Int 2014; 111(40):674-679. Medline


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