Agitation
Date Last Search Run: Jan 14, 2025
Table last updated: Dec 12, 2017
Data last added: Dec 18, 2017
Recommendation
RECOMMENDATION FOR INTERVENTION
STRENGTH OF EVIDENCE FOR INTERVENTION
 
SUPPORTIVE (Green)
NEUTRAL (Yellow)
AGAINST (Red)
NOT YET GRADED (White)
1 (strong evidence exists)
 
 
 
Benzodiazepines
Fans
Levomepromazine
Repositioning
2 (fair evidence exists)
 
 
 
3 (weak evidence exists)
Haloperidol
Ketamine
 
 
Interventions
Benzodiazepines
Level
Direction
Primary Outcome
Patient/Process
Setting
Reference
Fans
Level
Direction
Primary Outcome
Patient/Process
Setting
Reference
X
Not Yet Graded (White)
-
Puspawati N., Sitorus R., Herawatit T. Hand‑held Fan Airflow Stimulation Relieves Dyspnea in Lung Cancer Patients. Asia‑Pacific J of On Nursing 2017; 4:2.
Medline
Haloperidol
Level
Direction
Primary Outcome
Patient/Process
Setting
Reference
III
Supportive (Green)
Clinical benefit on delirium
Patient
In-Patient
Crawford G., Agar M., Quinn S., et al. Pharmacovigilance in Hospice/Palliative Care: Net Effect of Haloperidol for Delirium. J of Pall Med 2013; 16(11):1335-41.
Medline
Ketamine
Level
Direction
Primary Outcome
Patient/Process
Setting
Reference
III
Supportive (Green)
Sedation
Patient
ICU
Noreika DM., Coyne P. Discontinuance of life sustaining treatment utilizing ketamine for symptom management. J Pain Palliat Care Pharmacother 2015; 29(1):37-40.
Medline
Levomepromazine
Level
Direction
Primary Outcome
Patient/Process
Setting
Reference
Repositioning
Level
Direction
Primary Outcome
Patient/Process
Setting
Reference
[
PEP Database - Table of Contents
]
[
Email: PEP@Dal.ca
]